| dc.description.abstract | Bionanophotonics, a fusion of biology, nanotechnology, and Photonics,
fosters the development of devices and tools with dimensions on the
nanoscale, facilitating interactions at the level of biomolecular and cellular
structures. Nanomaterials are utilized in bionanophotonics to manipulate
light-matter interactions at the nanoscale within biological systems, enabling
advanced imaging, sensing, and therapeutic applications.
Template synthesis of nanomaterials involves using a pre-formed template to
guide the growth and organization of nanoscale structures with precise
control over size, shape, and composition. This study employs two templates
– DNA and a novel Schiff base ligand – for nanoparticle synthesis. DNA
templates excel in generating nanostructured photonic materials and
inorganic structures, showcasing potential for highly ordered nanostructures.
Schiff base ligands, cost-effective and environmentally friendly, are emerging
as templates for nanoparticle synthesis.
Comprehensive studies on DNA-capped CdS and Ag nanoparticles reveal
their diverse applications. The CdS nanoparticles demonstrate tunability in
the emission properties of rhodamine 6G dye, efficient photodegradation,
antibacterial activity, and Bioimaging applications. Silver nanoparticles
exhibit larvicidal, antibacterial effects, Bioimaging and fluorescence
enhancement in rhodamine 6G dye. Schiff base ligands, important in
coordination chemistry, form metal complexes with various biological and
catalytic applications. A novel Schiff base ligand and its Ni (II) complex were
synthesized. They show semiconductor properties and biological activities.
CdS nanoparticles were also synthesized by using the Schiff base as a
template. It also shows photocatalytic activity and different biological
applications like antibacterial and bioimaging. Both the CdS show green
fluorescence in bioimaging of HeLa cells (cervical cancer cells), while the Ag
nanoparticles show red fluorescence. Moreover, Schiff base ligands are
employed in metal sensors utilizing absorption and fluorescence spectra,
offering promising prospects in environmental monitoring and biomedical
diagnostics. A solid metal sensing device has also been fabricated using a thin
film made of Schiff base, with Raman spectrum assistance. In conclusion,
this research opens avenues for advancements across various fields.
Nanophotonics and nanomaterials offer solutions for healthcare and
biotechnology challenges, using DNA templates and Schiff base ligands in
nanoparticle synthesis and metal sensing. Collaborative interdisciplinary
efforts are crucial for driving innovation and addressing complex issues in
materials science and healthcare. | en_US |
