Multifaceted Approach in the Photonic and Biological Applications of CdS and Ag Nanoparticles Engineered on DNA and Schiff Base Templates.

Abstract

Bionanophotonics, a fusion of biology, nanotechnology, and Photonics, fosters the development of devices and tools with dimensions on the nanoscale, facilitating interactions at the level of biomolecular and cellular structures. Nanomaterials are utilized in bionanophotonics to manipulate light-matter interactions at the nanoscale within biological systems, enabling advanced imaging, sensing, and therapeutic applications. Template synthesis of nanomaterials involves using a pre-formed template to guide the growth and organization of nanoscale structures with precise control over size, shape, and composition. This study employs two templates – DNA and a novel Schiff base ligand – for nanoparticle synthesis. DNA templates excel in generating nanostructured photonic materials and inorganic structures, showcasing potential for highly ordered nanostructures. Schiff base ligands, cost-effective and environmentally friendly, are emerging as templates for nanoparticle synthesis. Comprehensive studies on DNA-capped CdS and Ag nanoparticles reveal their diverse applications. The CdS nanoparticles demonstrate tunability in the emission properties of rhodamine 6G dye, efficient photodegradation, antibacterial activity, and Bioimaging applications. Silver nanoparticles exhibit larvicidal, antibacterial effects, Bioimaging and fluorescence enhancement in rhodamine 6G dye. Schiff base ligands, important in coordination chemistry, form metal complexes with various biological and catalytic applications. A novel Schiff base ligand and its Ni (II) complex were synthesized. They show semiconductor properties and biological activities. CdS nanoparticles were also synthesized by using the Schiff base as a template. It also shows photocatalytic activity and different biological applications like antibacterial and bioimaging. Both the CdS show green fluorescence in bioimaging of HeLa cells (cervical cancer cells), while the Ag nanoparticles show red fluorescence. Moreover, Schiff base ligands are employed in metal sensors utilizing absorption and fluorescence spectra, offering promising prospects in environmental monitoring and biomedical diagnostics. A solid metal sensing device has also been fabricated using a thin film made of Schiff base, with Raman spectrum assistance. In conclusion, this research opens avenues for advancements across various fields. Nanophotonics and nanomaterials offer solutions for healthcare and biotechnology challenges, using DNA templates and Schiff base ligands in nanoparticle synthesis and metal sensing. Collaborative interdisciplinary efforts are crucial for driving innovation and addressing complex issues in materials science and healthcare.